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ALS overview

The more you learn about ALS, the better prepared you’ll be. Remember, in addition to doing your research, speaking with your healthcare provider(s) regularly will help you make the most informed decisions moving forward.

Who gets ALS?

  • canada-map

    In an estimated Canadian population of
    34 million, approximately 2,000–3,000
    people in Canada currently have ALS.

  • users

    In any given year, about two new cases of
    ALS per 100,000 people will be diagnosed
    in Canada.

The relatively low prevalence is potentially understated due to the rapid progression of ALS.


The prevalence of ALS increases with age

Age distribution chart


Causes of ALS

The contributing factors for developing ALS are not fully understood. However, in some rare cases, ALS may be inherited. There are generally two types of ALS:

  • -

    Familial ALS

    Affects: 5% to 10% of people with ALS

    Cause: Hereditary 

  • -

    Sporadic ALS

    Affects: 90% to 95% of people with ALS

    Cause: Unknown

Risk factors among the Canadian population:

  • Common age of onset is between 40–70 years of age
  • ALS is diagnosed in both men and women of all ethnic and socio-economic groups
  • Sporadic ALS occurs more in men than in women (1.6:1)
  • Other risk factors include family history (genetic and heredity factors) and smoking

Research suggests many factors can contribute to the loss of motor neurons in the brain, which may include:

Neuron EN

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